Noticeable Effects of Adrafinil


Adrafinil is a drug with mild stimulant effects used to treat and/or manage mental sluggishness, fatigue, and sleepiness. The drug is also observed to increase an individual’s alertness and ability to focus, which is why it is also being studied for its potential as a cure for Attention Deficit Disorder (ADD) and Attention Deficit Hyperactivity Disorder (ADHD).

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The ability of Adrafinil to increase mental alertness and focus easily makes it a subject of interest among the community of nootropic users. Adrafinil has also shown the ability to stave off mental fatigue and at the same time give the brain an added boost of energy. This drug is apparently so effective that it was recently included in the list of banned substances by World Anti-Doping Agency (WADA).

Adrafinil was discovered more than four decades ago in France by scientists at Group Lafon, a pharmaceutical company that also developed Modafinil. Adrafinil is a pro-drug of Modafinil. To the uninitiated, a pro-drug refers to a substance that transforms into another while it is being metabolized. Therefore Adrafinil is taken in order for the individual to benefit from the effects of Modafinil.


One of the main differences of the effects of Adrafinil from Modafinil, is that it takes quite a bit of time for the effects of Adrafinil to be noticeable. On average a healthy individual can feel the stim effects of Adrafinil after at least 40 minutes to an hour after administration, which is significantly slower than Modafinil.

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While stimulants make one hyperactive and energetic, Adrafinil is different in the sense that it instead keeps sleepiness at bay. What Adrafinil may lack in terms of the speed at which its effects can be enjoyed, it certainly makes up for its long half-life. Based on lab tests, a single dosing of Adrafinil can stay in the system for five to seven hours after administration.

As a nootropic agent, the most obvious contribution of Adrafinil as a cognitive enhancer would be its ability to increase mental alertness, clarity, focus, and energy. Users often report of an increased ability to concentrate for a particularly long period of time without as much as suffering from mental fatigue. There are also users who report of having an increased ability to retain and recall new and unfamiliar data with ease. Adrafinil is also being touted as an effective antidepressant and an anxiolytic.

The effect of Adrafinil use on the liver is being closely monitored as it has been shown to raise the enzyme levels in the organ. Although this should be expected as Adrafinil is metabolized in the liver, medical experts are almost unanimous in advising against supplementing with Adrafinil for a protracted cycle. The known side effects from using Adrafinil include upset stomach, skin problems, anxiety, and depression.


  • It has decent nootropic effects.
  • It can improve alertness and focus.
  • It has a long half life.
  • It can double as an antidepressant and as an anxiolytic.
  • It can help improve physical performance


  • It may cause problems in the liver.
  • It has some unpleasant side effects.
  • It can disturb your sleep patterns and may even cause insomnia.

The recommended doses for Adrafinil supplementation is around 600 to 1,200mg taken around three times each week. It also needs to be taken very early in the morning, preferably after you wake up to ensure that it doesn’t mess up your sleeping patterns. It is always best to consult with your doctor before starting on a Adrafinil supplementation.

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