Pitolisant, A Wakefulness Enhancing Agent

Pitolisant is an H3 histamine receptor inverse agonist/antagonist and it is currently being studied for its potential as a treatment for schizophrenia and Parkinson’s disease. Its inhibiting action against the H3-receptor promotes wakefulness, alertness, and vigilance. This compound has been researched for the treatment of narcolepsy for which it has been granted an orphan drug […]

Ciproxifan – An Essential Type of Histamine Inhibitor

Ciproxifan, or cyclopropyl-(4-(3-1H-imidazol-4-yl)propyloxy) phenyl) ketone, is a novel compound belonging to a group of H3-receptor agonists. It is observed to be highly potent in current animal studies, which means that being a H3-receptor agonist, Ciproxifan has a very promising potential for medical and therapeutic use as a waking and a cognitive enhancing agent. Ciproxifan was […]