Although nefiracetam is one of the lesser known derivatives of the parent nootropic molecule piracetam, it has been steadily winning over nootropic users over the last few years. This may be attributed to the fact that most nootropic users generally prefer fast acting cognitive enhancers that affect memory retention in a single dose. On the other hand nefiracetam requires steady dosing for at least a week in order for its memory enhancing ability to take effect. Its structure closely resembles another piracetam derivative, aniracetam and they are both fat soluble and are known to be beneficial for memory enhancement.

NEFIRACETAMNefiracetam may not be as popular for users as other nootropics, but it has caught the attention of major pharmaceutical companies for its abilities to protect the brain and even reverse damages caused to it. Early clinical studies suggest that nefiracetam supplementation may have positive effects for people suffering from Alzheimer’s Disease, epilepsy, and amnesia. Nefiracetam supplementation has also been shown to speed up the recovery of stroke victims by reducing post-stroke apathy and increasing the motivation of stroke patients.

As a nootropic, nefiracetam does not produce a significant euphoric effect like other drugs, which probably explains why supplementing with it hasn’t caught on yet. As far as memory enhancement goes however, it is the only nootropic that has the ability to speed up the choline uptake in your neurons. Choline is essential in order for your brain to form the neurotransmitter acetylcholine, which makes memory retention, recall, and brain focus much more efficient.

While regular supplementation with nefiracetam is viewed as an inconvenience by some, its benefits are far more profound and significant compared to occasional dosing with other nootropics. The positive effects of nefiracetam on memory and cognitive function are more lasting and at the same time, prolonged use helps stave off cognitive decline due to age and other factors. Once you are on steady supplementation, nefiracetam becomes fast acting, affecting the brain in less than an hour. Among the known positive effects of nefiracetam supplementation include an increased ability to learn, enhanced memory retention and recall, and faster cognition.

Apart from regular dosing, perhaps one of the more legitimate gripes about nefiracetam has something to do with its availability, or the lack of it. Since demand for this drug is not as high as other nootropics, its supply is also limited. Its suppliers online are very few and the availability of their stocks are frustratingly unreliable. As for its side-effects, some users have reported experiencing recurring headaches, light-headedness, dizziness, and upset stomach. However, since studies on nefiracetam are limited, such side-effects can’t be conclusively attributed to the drug.


  • It has lasting positive effects.
  • Its prolonged use protects the brain.
  • Has minimal stimulant effect.
  • It’s known to delay cognitive decline.


  • Availability.
  • Requires steady supplementation.

The current established daily dose for nefiracetam supplementation is at 150 to 450mg divided into three, taken orally before each meal of the day. Taking a choline supplement like Alpha GPC has been proven to be helpful in preventing headaches that sometimes occurs when dosing with this drug. Although early studies show that humans can safely take as much as 950mg of nefiracetam daily, caution should be taken when supplementing with this drug.

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